Clinical orthopaedics and related research

What Is the Effect of Robot Reduction in Displaced Pelvic Fractures? A Multicenter Randomized Clinical Trial

Zhao C, Ge Y, Cao Q et al. · 2026 Jul 01
Study Type: Multicentre RCT (Level I evidence)
Key Question: Does robotic closed reduction improve reduction quality and reduce radiation exposure compared with manual closed reduction in displaced pelvic fractures?
Key Findings:
  • Robotic reduction achieved excellent/good reduction (Matta criteria) in 96% vs 48% with manual technique (RR 2.00, 95% CI 1.47–2.72; p<0.001)
  • Intraoperative surgeon fluoroscopic exposures were significantly lower with robotic reduction (median 0 vs 38; p<0.001)
  • No significant difference in 12-week Majeed functional scores (69 vs 71; mean difference −3, 95% CI −11 to 6; p=0.55)
Clinical Relevance: Robotic reduction offers substantially improved anatomical outcomes and reduced radiation burden for pelvic ring fractures, relevant to UK major trauma centres considering robotic platform investment.
Limitations: Short follow-up (12 weeks) limits conclusions on functional recovery, and the study was conducted in Chinese tertiary centres, limiting generalisability to NHS trauma systems without cost-effectiveness data.
Clinical orthopaedics and related research

Are Age-based Cutoffs for THA Logically Consistent?

Bernstein J, Lee A, Kandel L et al. · 2026 Jun 23
Study Type: Decision analysis (Markov state-transition model)
Key Question: Are age-based thresholds that restrict THA in younger patients logically consistent with its routine use in patients aged 85 and over?
Key Findings:
  • 45-year-old males are projected to accrue ~25 JALYs (joint-adequate life years) under base-case assumptions, far exceeding the 6-JALY benchmark derived from 85-year-old recipients
  • The 45-year-old cohort's expected benefit only falls below this threshold if revision carries a penalty exceeding 25 JALYs — an implausibly high value
  • Findings were robust across sensitivity analyses varying prosthetic survival, satisfaction rates, failure rates, and discount rates
Clinical Relevance: UK orthopaedic clinicians and commissioners who apply informal age-floor thresholds for THA should recognise these may lack logical basis; younger patients with disabling hip disease stand to gain substantially more lifetime benefit than older patients routinely offered the procedure.
Limitations: The model uses US life tables and theoretical constructs (JALYs) not validated against patient-reported outcome data, limiting direct clinical translation.
Clinical orthopaedics and related research

Clinical Presentation Patterns and Outcomes of Decompression for Suprascapular Neuropathy: A Retrospective Surgical Series

McCarthy CF, Bishop KR, Lansford JL et al. · 2026 Jun 23
Study Type: Retrospective case series (Level III)
Key Question: What are the clinical presentation patterns and outcomes of arthroscopic suprascapular nerve decompression in young, active patients without rotator cuff tear or space-occupying lesion?
Key Findings:
  • Two distinct presentations identified: pain-predominant (n=10, normal MRI/EMG) and weakness-predominant (n=10, all with MRI muscle oedema/atrophy and EMG denervation changes)
  • Pain-predominant group: median VAS improved from 6 to 1 (p=0.009); weakness-predominant group: abduction and external rotation motor grades improved significantly (both p<0.01)
  • 17/20 patients (85%) returned to military duty or sport at median 13 weeks, sustained beyond one year
Clinical Relevance: Suprascapular neuropathy is likely under-diagnosed in active patients with unexplained shoulder pain or weakness; this series supports a structured diagnostic algorithm and arthroscopic decompression as an effective intervention.
Limitations: Small single-centre series (n=20) in a predominantly young military male population limits generalisability to typical NHS shoulder caseloads.
Clinical orthopaedics and related research

Are Social Determinants of Health Disparities Associated With Worse Completion Rates for Patient-reported Outcome Measures After Total Joint Arthroplasty?

Meacock S, Hohmann A, Sellig MT et al. · 2026 Jun 24
Study Type: Retrospective comparative cohort study (single institution, Level III prognostic)
Key Question: Do social determinants of health (SDOH) disparities — including race, insurance type, transportation access, living alone, and neighbourhood deprivation indices — affect PROMs completion rates following total joint arthroplasty?
Key Findings:
  • Across 12,842 TJA patients, no clinically important differences (defined as ≥15% change) in PROM completion were identified based on race, transportation access, living alone, or insurance type at any timepoint.
  • Neighbourhood-level deprivation scores (ADI and SVI) showed statistically significant but clinically negligible differences between completers and non-completers.
  • Statistically significant p-values were present throughout but did not meet the pre-specified threshold for clinical importance.
Clinical Relevance: As NHS England expands PROM requirements for elective arthroplasty, these findings suggest common SDOH factors may not substantially drive completion gaps, though generalisability beyond a US urban academic centre requires caution.
Limitations: Single-institution US dataset with a predominantly White cohort (86%) limits generalisability to diverse NHS patient populations.
Clinical orthopaedics and related research

What Are the Substantial Clinical Benefit Thresholds for KOOS Pain, Physical Function, and Joint Replacement Scores After Primary TKA?

Elmenawi KA, Pasqualini I, Khan ST et al. · 2026 Jun 25
Study Type: Retrospective cohort analysis (Level III)
Key Question: What are the SCB thresholds for KOOS subscales after primary TKA, and which patient factors predict failure to achieve them?
Key Findings:
  • SCB thresholds were 33/100 (KOOS Pain), 16/100 (KOOS PS), and 23/100 (KOOS JR); only 59% of patients achieved these at one year
  • Non-White race was consistently the strongest predictor of SCB non-attainment across all subscales (OR ~1.7–1.8), alongside older age, higher comorbidity burden, and lower education level
  • AUC values (0.69–0.72) indicate moderate discriminative ability of these anchor-based thresholds
Clinical Relevance: Although US CMS reimbursement policy drives this study, NHS England's increasing use of PROMs for TKA quality benchmarking makes understanding SCB thresholds and equity-related outcome disparities directly relevant to UK arthroplasty services.
Limitations: Single-institution US registry data with ~21% loss to follow-up may limit generalisability to NHS populations with differing demographics and healthcare structures.
Clinical orthopaedics and related research

Radial Head Fractures Cluster in the Anterolateral and Anteromedial Quadrants and Do Not Correlate With Coronoid Fracture Types

Azib N, de Klerk HH, Doornberg JN et al. · 2026 Jun 26
Study Type: Retrospective multicentre descriptive study (secondary data analysis; Level IV)
Key Question: In combined coronoid and radial head fractures, what radial head fracture patterns predominate, and do they correlate with coronoid fracture type?
Key Findings:
  • The commonest radial head fracture pattern was a single fragment spanning both anterolateral and anteromedial quadrants (31%; 51/167), with most fractures comprising a single fragment overall (49%)
  • No statistically significant association was found between radial head fracture pattern and O'Driscoll coronoid fracture type
  • Interrater reliability was substantial for both quadrant mapping (κ=0.715) and O'Driscoll classification (κ=0.658)
Clinical Relevance: These findings support treating radial head and coronoid fractures as independent injury components during preoperative CT planning and intraoperative assessment, rather than inferring one from the other — relevant to surgical approach selection in terrible triad and complex elbow instability cases.
Limitations: Retrospective Level IV design from two tertiary trauma centres limits generalisability and introduces selection bias.
Clinical orthopaedics and related research

Reduced Cerebellar Activation With Eyes Closed Is Associated With Delayed Peroneal Reaction Time in Patients With Chronic Ankle Instability

Hou Z, Zeng X, Huang W et al. · 2026 May 20
Study Type: Cross-sectional study
Key Question: Does cerebellar activation differ between patients with chronic ankle instability (CAI) and controls across visual conditions, and does this relate to neuromuscular deficits?
Key Findings:
  • CAI patients showed significantly reduced cerebellar activation (lobule VI, vermis VI, crus I) when transitioning from eyes-open to eyes-closed during ankle movement tasks (group mean differences ranging −21.7 to −26.6 voxels, all p<0.001)
  • Reduced cerebellar and fusiform gyrus activation correlated moderately with delayed peroneal reaction time (eyes-open: r=−0.38; eyes-closed: r=−0.40, both p<0.05) and worse self-reported function (CAIT, ALR-RSI)
  • No association was found between cerebellar activation and static postural stability (Romberg ratio)
Clinical Relevance: Central sensorimotor deficits, not purely peripheral, underpin CAI — suggesting rehabilitation programmes should incorporate vision-manipulation and cerebellar-targeted tasks rather than focusing solely on peripheral proprioception.
Limitations: Small sample size (n=35) limits generalisability and statistical power for subgroup analyses.
The American journal of sports medicine

Two-Year Outcomes of the Proximal Hamstring Avulsion Rehabilitation Regimes: Longitudinal Versus Accelerated Protocol (PHARRLAP) Study: A Randomized Controlled Trial

Ebert JR, Edwards PK, Cecchi S et al. · 2026 Jun 21
Study Type: Randomised Controlled Trial (Level 1 evidence)
Key Question: Does accelerated rehabilitation (full weightbearing, no bracing) produce equivalent outcomes to conservative rehabilitation (6-week bracing, restricted weightbearing) following surgical repair of acute proximal hamstring avulsion involving ≥2 tendons?
Key Findings:
  • Accelerated rehabilitation showed better SF-12 physical scores at 3 months (p=0.039) and lower hamstring pain severity at 3 and 12 months (p=0.034; p=0.010), but no significant differences in strength or hop test outcomes at any timepoint
  • Isokinetic strength and single-leg hop performance improved significantly in both groups across 24 months (all p<0.001)
  • Overall rerupture rate was 7% (4/57), evenly distributed between groups
Clinical Relevance: This supports omitting post-operative bracing and early full weightbearing following proximal hamstring repair, which has practical implications for patient comfort and NHS rehabilitation resource utilisation.
Limitations: The trial was underpowered to detect meaningful differences in rerupture rates between protocols.

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